Jefferson County is linked by a modern network of highway and railway systems and is the only county to have a full service airport located along an interstate highway.
U.S. Interstate 80, also known as the Keystone Shortway, crosses the middle of Jefferson County for 36 miles from west to east with four intersections with major state and federal highways. I-80 provides residents and businesses easy access to many of the country’s major metropolitan areas and second tier cities.
Exits include 73 at Corsica, 78 at Brookville/Sigel, 81 at Hazen and 86 at Reynoldsville. Principal interstate highways passing through the county include U.S. Route 119, 219 and 322, plus State Routes 28, 36, 536, 830, 949 and 950.